Research Progress on Chemical Constituents,Pharmacological Effects and Preparation Methods of Bolenggua(Herpetospermum caudigerum)and Prediction Analysis on Quality Markers
Bolenggua(Herpetospermum caudigerum),as an important resource of medicinal plants,has the efficacy of clearing heat and detoxicating and soothing liver and gallbladder.It mainly includes fatty acid,coumarin,polysaccharide,lignan and other chemical components.It has the functions of anti-hepatic injury,anti-hepatitis B virus,anti-liver fibrosis,anti-tumor,anti-inflammatory and so on.Chemical composition,main pharmacological activities and formulation development of Bolenggua(Herpe-tospermum caudigerum)were summarized in this paper.What's more,based on quality marker(Q-marker)theory of traditional Chinese medicine,the Q-marker of Bolenggua(Herpetospermum caudigerum)was predicted and analyzed from the aspects of phylogenetic relationship and specificity of chemical components,traditional medicinal property and efficacy,compound compati-bility environment,chemical composition measurability,processing-related and blood components,etc.The result indicated that the possible Q-markers could be regarded as the dehydrodiconiferyl alcohol,herpetotriol,herpetolide A,herpetrione,herpetin,herpetone,herpetfluorenone and herpetenol.This review provided a reference for the establishment of quality evaluation system of Bolenggua(Herpetospermum caudigerum).
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