首页|枸杞化学成分和药理作用研究进展及质量标志物的预测分析

枸杞化学成分和药理作用研究进展及质量标志物的预测分析

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枸杞是一种药食两用药材,被广泛应用于保健食品的加工中.研究表明其含有多糖类、黄酮类、花色苷类、原花青素类、生物碱类等多种化学成分,且具有免疫调节、抗衰老、降糖调脂、降压、抗肿瘤等药理作用.通过对枸杞的主要化学成分和药理作用进行综述,在此基础上,结合质量标志物(Q-marker)理论的研究思路,从传统功效、植物亲缘学、化学成分有效性等方面进行枸杞质量标志物预测,为枸杞的进一步开发利用提供科学依据.
Research Progress of Gouqi(Lycium barbarum)and Predictive Analysis on Its Q-markers
Gouqi(Lycium barbarum)is a kind of plant with dual use of medicine and food,and is widely used in health food processing.Studies show that it contains polysaccharide,flavonoids,anthocyanins,procyanidins,alkaloids and other chemical components.It contains various chemical components such as polysaccharides,flavonoids,anthocyanins,proanthocyanidins and alkaloids,and has pharmacological effects such as immune regulation,anti-aging,hypoglycemic and lipid-lowering,antihyper-tensive and anti-tumor effects.This article reviewed the main chemical components and pharmacological effects of Gouqi(Lyci-um barbarum).Based on this,combined with the research ideas of quality marker(Q-marker)theory,it predicted the Q-markers of Gouqi(Lycium barbarum)from traditional efficacy,plant phylogeny,chemical component effectiveness and other as-pects,providing scientific basis for the further development and utilization of Gouqi(Lycium barbarum).

Gouqi(Lycium barbarum)Lycium barbarum polysaccharideflavonoidsanthocyaninsproanthocyanidinsalka-loidsquality marker

张雪燕、戴瑜婷、王艺璇、何洋、何廷伟、刘永琦、和建政、修明慧

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甘肃中医药大学公共卫生学院,甘肃兰州 730000

甘肃中医药大学第一临床医学院,甘肃兰州 730000

甘肃中医药大学,甘肃省高校重大疾病分子医学与中医药防治研究重点实验室,甘肃兰州 730000

甘肃中医药大学,敦煌医学与转化教育部重点实验室,甘肃兰州 730000

甘肃中医药大学基础医学院,甘肃兰州 730000

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枸杞 枸杞多糖 黄酮类 花色苷类 原花青素类 生物碱类 质量标志物

国家自然科学基金青年科学基金项目国家自然科学基金青年科学基金项目甘肃省教育厅高等学校产业支撑计划项目

82004228821045622020C-15

2024

中华中医药学刊
中华中医药学会 ,辽宁中医药大学

中华中医药学刊

CSTPCD北大核心
影响因子:1.007
ISSN:1673-7717
年,卷(期):2024.42(1)
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