摘要
经皮冠状动脉介入术(percutaneous coronary intervention,PCI)是目前最有效的再灌注方式,但心肌梗死(myo-cardial infarction,MI)患者在术后发生不良心血管事件的风险仍然较高,这种现象与冠脉微循环障碍(coronary microvas-cular dysfunction,CMD)密切相关.目前已提出很多诊疗策略防治冠脉微循环障碍,但常规西药治疗效果并不显著,不良心血管事件的发生率居高不下,仍缺乏有效的治疗方案.多项研究表明,中药对冠状动脉介入术后冠脉微循环障碍有显著疗效.概述中医药治疗冠状动脉介入术后冠脉微循环障碍的相关研究进展,以期为冠状动脉介入术后冠脉微循环障碍提供新的治疗思路.
Abstract
Percutaneous coronary intervention(PCI)is currently the most effective reperfusion method,but the patients with myocardial infarction(MI)are still at high risk of adverse cardiovascular events after PCI surgery.This phenomenon is closely re-lated to coronary microvascular dysfunction(CMD).Many diagnosis and treatment strategies have been proposed,but the effect of conventional western medicine treatment is not significant.The incidence of major adverse cardiovascular events remains high,and there is still a lack of effective treatment plan.A number of studies have shown that traditional Chinese medicine has a signif-icant effect on postoperative microcirculation disease after PCI.This article summarized the relevant mechanism of traditional Chi-nese medicine in the treatment of CMD after PCI in order to provide new treatment ideas for CMD after PCI surgery.
基金项目
国家重点研发计划-中医药现代化专项(2019YFC1710001)
国家重点研发计划-中医药现代化专项(2019YFC1710000)
国家自然科学基金重点项目(82030120)
河南省中医药科学研究专项(2018JDZX009)
NETL
NSTL
万方数据