摘要
血脂异常可增加脑卒中的发病率.血脂异常和脑卒中在中医学中分别属于"肥人"和"中风"范畴,二者的主要发病机制为膏脂运化失常,聚生痰浊血瘀等实邪阻滞络脉导致中风."络病理论"起源于《黄帝内经》,是中医学辨证论治诊治疾病的重要理论之一.基于该理论,认为血脂异常合并中风的病程分为络脉空虚、风痰侵袭、络脉不通,痰火瘀闭、络脉虚损,毒邪肆虐3个阶段,对应治则分别为补肺脾肾,益气通络、泻火化痰、祛瘀通络、解毒通络、醒神固脱.围绕络病理论概述、从络病理论诠释分析血脂异常合并中风的病机和治疗3个方面展开,以期为临床改善血脂异常治疗中风提供理论参考.
Abstract
Dyslipidemia can increase the incidence rate of apoplexy.In traditional Chinese medicine,dyslipidemia and apo-plexy belong to the categories of"fat person"and"stroke",respectively.The main pathogenesis of both is dyslipidemia of fat,accumulation of phlegm and blood stasis,and other excess pathogenic factors that block collaterals,leading to stroke.The theory of collateral disease is originated from Huangdi Neijing and is one of the important theories for the diagnosis and treatment of dis-eases based on syndrome differentiation in traditional Chinese medicine.Based on this theory,the author believes that the course of dyslipidemia combined with stroke can be divided into three stages:deficiency of collaterals,invasion of wind and phlegm,blockage of collaterals,closure of phlegm,fire and blood stasis,deficiency and damage of collaterals and rampant toxin.The corre-sponding treatment principles are respectively reinforcing lung,spleen and kidney,supplementing Qi and clearing collaterals,pur-ging fire and resolving phlegm,removing blood stasis and clearing collaterals,detoxifying and clearing collaterals,awakening the mind and consolidating the body.This article focused on the overview of collateral disease theory,and analyzed the pathogenesis and treatment of dyslipidemia combined with stroke from the perspective of collateral disease theory,so as to provide the theoreti-cal reference for clinical improvement of dyslipidemia and treatment of stroke.
基金项目
国家自然科学基金(81974548)
国家自然科学基金(82074145)
辽宁省教育厅基本科研项目(青年项目)(LJKQZ2021066)
辽宁省教育厅基本科研项目(面上项目)(LJKMZ20221337)
辽宁省高等学校黄大年式教师团队项目()
辽宁中医药大学自然科学研究重点项目(2021LZY050)