首页|内关穴和足三里穴位刺激对腹腔镜结直肠癌根治术麻醉及术后胃肠功能的影响

内关穴和足三里穴位刺激对腹腔镜结直肠癌根治术麻醉及术后胃肠功能的影响

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目的 观察内关穴和足三里穴位刺激对腹腔镜结直肠癌根治术麻醉及术后胃肠功能的影响。方法 以2021年1月—2022年6月医院进行腹腔镜结直肠癌根治术的患者126例作为研究对象,通过随机数表法分为两组,每组63例,对照组术后常规镇痛干预,观察组在对照组基础上进行内关穴和足三里穴位刺激,比较两组的麻醉术后恢复、胃肠功能及免疫功能情况和不良反应发生率,观察指标包括疼痛视觉模拟评分法(Visual Analogue Scale,VAS)、拉姆齐(Ramsay)镇静评分,胃肠反应分级,肠鸣音恢复时间、肛门排气时间、进食流质饮食时间、排便时间,外周血T淋巴细胞亚群(CD3+、CD4+、CD8+)及自然杀伤细胞(natural killer cell,NK),不良反应。结果 术后24、48 h观察组VAS评分显著低于对照组,差异均有统计学意义(P<0。05),Ramsay评分差异无统计学意义(P>0。05)。术后48 h观察组胃肠反应分级显著优于对照组,差异有统计学意义(P<0。05)。两组肠鸣音恢复时间、肛门排气时间、进食流质饮食时间比较差异有统计学意义(P<0。05),观察组均短于对照组。术后5 d两组CD3+、CD4+、NK水平均显著升高,且观察组高于对照组,差异有统计学意义(P<0。05),但两组CD8+变化不明显,差异无统计学意义(P>0。05)。观察组不良反应发生率为9。53%,对照组不良反应发生率为14。29%,组间差异无统计学意义(P>0。05)。结论 内关穴和足三里穴位刺激有利于腹腔镜结直肠癌根治术患者麻醉及术后恢复,镇痛、镇静效果良好,胃肠功能恢复更快,提高患者免疫功能,利于术后康复。
Effect of Stimulation of Neiguan(PC6)and Zusanli(ST36)on Anesthesia and Postoperative Gastrointestinal Function in Laparoscopic Radical Resection of Colorectal Cancer
Objective To observe the effect of the stimulation of Neiguan(PC6)and Zusanli(ST36)on anesthesia and postop-erative gastrointestinal function in laparoscopic radical resection of colorectal cancer.Methods A total of 126 patients who under-went laparoscopic radical resection of colorectal cancer in a hospital from January 2021 to June 2022 were enrolled in the study.They were divided into two groups by random number table method,63 cases in each group.The control group received routine postoperative analgesia intervention,and the observation group received the stimulation of Neiguan(PC6)and Zusanli(ST36)on the basis of the control group.The recovery after anesthesia,gastrointestinal function,immune function and incidence of adverse reactions were compared between the two groups.The observation indexes included visual analogue scale(VAS),sedation(Ram-say)score,gastrointestinal reaction grading,recovery time of bowel sounds,anal exhaust time,eating liquid diet time,defecation time,peripheral blood T lymphocyte subsets(CD3+,CD4+,CD8+)and natural killer cells(NK)and adverse reactions.Results The VAS scores of the observation group were significantly lower than those of the control group at 24 and 48 hours after operation,and the differences were statistically significant(P<0.05).48 h after operation,the gastrointestinal reaction grade of the observation group was significantly better than that of the control group,and the difference was statistically significant(P<0.05).There were significant differences in the recovery time of bowel sounds,anal exhaust time and liquid diet time between the two groups(P<0.05),and the time of the observation group was shorter than that of the control group.The levels of CD3+,CD4+and NK in the two groups were significantly increased 5 days after operation,and the levels of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05),but the changes of CD8+in the two groups were not obvi-ous,and there was no significant difference between the two groups(P>0.05).The incidence of adverse reactions was 9.53%in the observation group and 14.29%in the control group.There was no significant difference between the two groups(P>0.05).Conclusion The stimulation of Neiguan(PC6)and Zusanli(ST36)is beneficial for anesthesia and postoperative recovery of patients undergoing laparoscopic radical resection of colorectal cancer.The analgesic and sedative effects are good,the recov-ery of gastrointestinal function is faster,the patients immune function is improved,and the postoperative recovery is beneficial.

colorectal cancerlaparoscopyNeiguan(PC6)Zusanli(ST36)acupoint stimulationradical surgeryanesthesiagastrointestinal function

汪金娇、师建慧、李永坤

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南阳医学高等专科学校第一附属医院,河南南阳 473058

结直肠癌 腹腔镜 内关穴 足三里 穴位刺激 根治术 麻醉 胃肠功能

国家中医药局中医药科学技术研究专项

2019ZX785639

2024

中华中医药学刊
中华中医药学会 ,辽宁中医药大学

中华中医药学刊

CSTPCD北大核心
影响因子:1.007
ISSN:1673-7717
年,卷(期):2024.42(3)
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