Analysis of Medication Rules and Clinical Efficacy in Traditional Chinese Medicine for Treatment to Mild Symptoms with COVID-19
Objective To study the medication pattern and efficacy analysis of 83 patients with mild symptoms with corona vi-rus disease 2019(COVID-19)in Dandong,Liaoning.Methods A total of 83 patients with mild symptoms with COVID-19 ad-mitted to the Sixth People's Hospital of Dandong,Dandong Tuberculosis Hospital and Vocational College Square Cabin from June 5,2022 to June 18,2022 were collected.Frequency analysis,correlation analysis,cluster analysis and regression analysis were performed on the data based on Excel and SPSS.Results A total of 83 prescriptions involving 103 Chinese medicines were includ-ed,with a total of 1523 times.The top 10 drugs in terms of frequency of use were Pugongying(Taraxaci Herba),Chaihu(Bupleuri Radix),Gancao(Glycyrrhizae Radix Et Rhizoma),Kuxingren(Armeniacae Semen Amarum),Jiegeng(Platycodonis Radix),Yiy-iren(Coicis Semen),Huangqin(Scutellariae Radix),Maidong(Ophiopogonis Radix),Jinyinhua(Lonicerae Japonicae Flos)and Muxiang(Aucklandiae Radix).The top 3 frequencies of the four Qi of the drugs were cold,warm and flat.The top 3 flavors of the drugs were bitter,sweet and pungent.The top 3 frequency of meridian tropism were lung meridian,stomach meridian and spleen meridian.The top 3 frequencies of drug efficacy were clearing heat and removing toxins,relieving stranguria and promoting urination and draining dampness.The association rules were analyzed for the prescribed high-frequency Chinese medicines,and the effect of Gancao(Glycyrrhizae Radix Et Rhizoma)on the associated medicines was excluded,which showed that there were significant associations among Pugongying(Taraxaci Herba),Chaihu(Bupleuri Radix),Kuxingren(Armeniacae Semen Amarum)and Jiegeng(Platycodonis Radix).Through cluster analysis,5 types of drugs were identified.Through regression analysis,it is shown that for every additional day of nucleic acid positivity before medication,the likelihood of a nucleic acid positivity of ≥4 d after taking traditional Chinese medicine will increase by 37.4％.Conclusion The TCM treatment of COVID-19 mild infection should start with lung,stomach and spleen,focusing on clearing heat and detoxifying,combining with clearing damp-heat,regula-ting Qi and resolving phlegm,promoting lung and relieving cough and strengthening Qi and Yin.Early and timely intervention is the key to the efficacy.
万方数据
维普
