首页|鹿茸肽的提取纯化、药理作用、载体应用研究进展

鹿茸肽的提取纯化、药理作用、载体应用研究进展

扫码查看
由中药鹿茸中提取的鹿茸肽(VAP)具有抗骨损伤、抗肿瘤、抗神经疾病、抗氧化、抗炎、保护五脏、促进创面愈合等多种作用,是鹿茸的重要生物活性成分之一。系统综述VAP的提取、分离纯化方法,总结当前已知VAP的化学组成、结构。另外,还综述了 VAP相关载体新剂型的研究进展,将VAP与某些高分子材料结合,使之增加药理活性或减少不良反应,为VAP及其载体应用的进一步研究提供了基础。
Research Progress in Extraction and Purification,Pharmacological Action and Carrier Application of Pilose Antler Peptide
The pilose antler peptide(VAP)extracted from traditional Chinese medicine Lurong(pilose antler)has many functions,such as anti-bone injury,anti-tumor,anti-nerve disease,anti-oxidation,anti-inflammatory,protection of the five viscera and promotion of wound healing.It is one of the important bioactive components of Lurong(pilose antler).This paper systematically reviewed the methods of extraction,separation and purification of VAP,and summarized the chemical composition and structure of known VAP.In addition,this paper also reviewed the research progress of new dosage forms of VAP related carri-ers.Combining VAP with some polymer materials to increase pharmacological activity or reduce adverse reactions provided a ba-sis for further research of VAP and its carrier application.

pilose antler peptideextractionpurificationpharmacological actiondrug carrier

王清泉、宋景、王雨晴、魏玉民、董伟超、李晓雨、孙志强、代龙

展开 >

山东中医药大学药学院,山东济南 250355

山东禹泽药康产业技术研究院有限公司,山东德州 251200

鹿茸肽 提取 纯化 药理作用 载体应用

国家中医药局中医药高质量发展协同创新转化工程项目

CX2H202201

2024

中华中医药学刊
中华中医药学会 ,辽宁中医药大学

中华中医药学刊

CSTPCD北大核心
影响因子:1.007
ISSN:1673-7717
年,卷(期):2024.42(5)