Research Progress on Anti-Tumor Effects and Mechanisms of Maidong(Ophiopogonis Radix)
Maidong(Ophiopogonis Radix),as a traditional Chinese drug,has the effect of nourishing Yin,promoting body flu-id production,moistening lung,easing the mind and clearing away heart fire.Accumulated evidence has revealed that Maidong(Ophiopogonis Radix)is involved in inhabitation of a set of malignant tumors in addition to its traditional effects.It exerts anti-tumor effects by inhibiting cell proliferation,inducing apoptosis,necroptosis,ferroptosis,pyroptosis,autophagy and cell cycle ar-rest,inhibiting metastasis and angiogenesis and reversing drug resistance.This review summarized the antitumor effects of Maid-ong(Ophiopogonis Radix)tuber extract and its active monomer to provide a reference for further research and its development and utilization.
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