Effect of Quyu Xiaozhong Decoction(祛瘀消肿汤)on Postoperative Wound Healing of Mixed Hemorrhoids Based on Theory of Four Natures,Five Flavors and Meridian Tropism of ChineseMedicine
Objective To discuss the effect of Quyu Xiaozhong Decoction(祛瘀消肿汤)on postoperative wound healing of mixed hemorrhoids based on the theory of four natures,five flavors and meridian tropism of ChineseMedicine.Methods Ninety-eight patients with mixed hemorrhoids in the hospital from January 2021 to December 2022 were enrolledand classified into two groups by random number table methods,49 cases in each.The control group received surgical treatment of externol stripping and internal ligation.Based on this,the observation group was given Quyu Xiaozhong Decoction.The levels of serum inflammatory factors[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive Protein(CRP)],visual analogue scale(VAS)score,edema score and the levels of the wound healing and growth factors[basic fibroblast growth factor(b-FGF),vascular en-dothelial growth factor(VEGF)]were detected in two groups before and after treatment.The clinical efficacy and symptom remis-sion time were observed.Results The levels of serum IL-6,TNF-α and CRP,VAS score,edema score as well as the levels of b-FGF and VEGFyielded no statistical difference between two groups before treatment(P＞0.05).After treatment,there was a decrease inthe above three inflammation factors,VAS score and edema score,and an increase in the levels of b-FGF and VEGF in two groups,and both the decrease and increase in the observation group were more remarkable than those in the control group(P＜0.05).The wound bleeding score and wound exudation score denoted no statistical difference between two groups at post-treatment 10 days(P＞0.05),while these scores were significantly lower in the observation group than those in the control group at post-treatment 14 d(P＜0.05).After treatment,the relief time of anal bulging,anal edema,wound exudation disappearance time and pain relief time were shorter in the observation group than those in the control group,with statistical difference(P＜0.05).The overall efficacy rate was 95.92％(47/49)in the observation group,which was higher than 81.64％(40/49)in the control group,with statistical difference(x2=5.018,P=0.025).Conclusion Under the guidance of the theory of nature,taste and meridian tropism of traditional Chinese medicine,Quyu Xiaozhong decoction can reduce the level of serum inflammatory fac-tors after mixed hemorrhoids surgery,reduce wound pain,accelerate healing time and improve clinical efficacy.
natures,flavors and meridian tropismQuyu Xiaozhong Decoction(祛瘀消肿汤)mixed hemorrhoidswound healinggrowth factorsclinical efficacy
万方数据
维普
