Research Progress on Chemical Constituents and Pharmacological Effects of Chenpi(Dried Tangerine Peel)
Chenpi(dried tangerine peel)is the mature and dry peel of Ju(Citrus reticulata Blanco)and its cultivated varie-ties.It was first recorded in Shennong Bencao Jing.It is an important medicine for the treatment of phlegm and dampness,and also a source of medicinal and edible food.With the discovery of new chemical constituents and pharmacological effects of Chenpi(dried tangerine peel),the chemical constituents and pharmacological effects of Chenpi(dried tangerine peel)were reviewed and analyzed.The results showed that Chenpi(dried tangerine peel)mainly involved flavonoids,alkaloids,triterpenoids,volatile oils and other nearly hundreds of components,mainly including anti-inflammatory,anti-cancer,anti-obesity,anti-Aizheimer's disease,anti-Parkinson's disease,regulating blood vessels,protecting bones,protecting skin and other pharmacological effects.However,there are still some problems,such as the weak relationship between the chemical components in Chenpi(dried tange-rine peel)and the processing theory of long-term dried products with better quality,and the weak relationship between the chemical components and the pharmacological effects;there are still gaps in the Chinese Pharmacopoeia on the aging year,aging method and processing quality standard of Chenpi(dried tangerine peel).The pharmacological mechanism and pharmacodynamic material basis are not clear,most of which are extracts;in view of the problems existing in the research of Chenpi(dried tangerine peel),some suggestions are put forward for the high-quality development of Chenpi(dried tangerine peel):the quality standard of Chenpi(dried tangerine peel)aging should be formulated to reveal the scientific connotation of long-term dried products with better quality;to clarify the material basis of the efficacy of Chenpi(dried tangerine peel)and further explore the clear pharmaco-logical mechanism;to establish a comprehensive quantitative mechanism of composition-processing theory-storage method-ori-gin-efficacy in line with the characteristics of aging of Chenpi(dried tangerine peel),so as to clarify the evolution law of the fi-nal pharmacodynamic effect of Chenpi(dried tangerine peel).This paper aims to provide scientific basis for the research and de-velopment of new drugs containing Chenpi(dried tangerine peel),the study of pharmacodynamic mechanism and the development of functional foods.