Research Progress in Chemical Constituents and Biological Activities of Cornel Iridoid Glycosides
Shanzhuyu(Corni Fructus)is one of the major medicinal materials for Chinese medicine and food,and is widely used in various patients of internal medicine,surgery,gynecology,pediatrics and the development of health care products.The cornel iridoid glycosides(CIG)is the characteristic active ingredient groups.The literature reports in the past 10 years has repor-ted that 103 kinds of CIG have been separated and identified.In this study,the chemical composition,fragmentation pattern and the study of metabolites in vivo of CIG were summarized,and the pharmacological research progress of CIG in hypoglycemia,neu-roprotection,cardiac protection,liver protection,kidney protection,testis protection and other biological activities were reviewed from the aspects of efficacy,action pathway and molecular mechanism.It is expected to provide new ideas for the further re-search,development and application of CIG.
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