Research Progress of Chinese Patent Medicines in Treatment of Primary Liver Cancer
Primary liver cancer,a prevalent refractory tumor,has poor prognosis,low quality of life and high recurrence rate in the patients in advanced stage.With the second mortality rate in China,primary liver cancer seriously threatens the life safety of patients with chronic liver disease.Traditional Chinese medicine has demonstrated advantages in the treatment of primary liver cancer.Chinese patent medicine boasts the advantages of convenient administration and high compliance,rendering it a promising candidate for extensive clinical applications.It possesses positive advantages in the management of primary liver cancer,particu-larly in ameliorating symptoms and enhancing quality of life,mitigating toxicities and side effects,augmenting the efficacy of com-bined therapy,prolonging patient survival time and reducing recurrence rates.Mechanistically,Chinese patent medicine can regu-late the internal and external environment of tumor cells,including the immune microenvironment and intestinal flora,metabolic patterns,growth and proliferation of tumor cells,molecular modification of liver cancer cells,invasion and metastasis inhibition as well as induction of tumor cell death.This article summarized the potential therapeutic effects of Chinese patent medicines on pri-mary liver cancer.Moreover,it summarized the mechanism and characteristics of Chinese patent medicines in primary liver canc-er treatment from relevant clinical and experimental research reports.It is expected to provide an idea for the exploration of tradi-tional Chinese medicine treatment strategies and new drug development for primary liver cancer therapy.
万方数据
维普
