Objective To explore the correlation between physical parameters and chemical composition of Baifuzi(Typhonii Rhizoma)standard decoction and establish models so as to use physical properties parameters to indicate intrinsic chemical com-position and provide reference for rapid quality evaluation of standard decoctions.Methods Standard decoction for Baifuzi(Typho-nii Rhizoma)raw and processed products was prepared.The physical parameters(relative density,pH value and oxidation value)were measured.The contents of starch,total polysaccharide and total flavone were determined by ultraviolet spectrophotometry.The contents of nucleosides and organic acids were determined by high performance liquid chromatography.The entropy weight TOPSIS objective weighting method was used to establish a multi-index comprehensive score,SPSS 21.0 software was used to conduct correlation analysis of physical parameters,chemical composition and comprehensive scores of Baifuzi(Typhonii Rhizo-ma)standard decoction,and the corresponding regression model was established.Results Correlation analysis showed that the physical parameters of Baifuzi(Typhonii Rhizoma)standard decoction were significantly correlated with the chemical composi-tion,among which pH value and relative density were the two physical parameters most correlated with the intrinsic chemical com-position.There was a significant negative correlation between comprehensive score and relative density.It was positively correla-ted with pH value and oxidation value.The models established by regression analysis had high fitting degree and were effective.Conclusion In this study,the physical parameters and the content of large and small molecule components of Baifuzi(Typhonii Rhizoma)standard decoction were comprehensively investigated,the physical parameters were significantly correlated with the chemical components and the regression models established were all highly fit,indicating the feasibility of using physical parame-ters to indicate the internal chemical components and providing a certain reference basis for the rapid quality evaluation and con-trol of Baifuzi(Typhonii Rhizoma)standard decoction.
维普
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