Clinical Study on Shensong Yangxin Capsule(参松养心胶囊)in Treatment of Senile Chronic Heart Failure
Objective To observe the clinical therapeutic effect of Shensong Yangxin Capsule(参松养心胶囊)on elderly pa-tients with chronic heart failure.Methods A total of 108 patients with chronic heart failure admitted to Beijing Shijitan Hospital Affiliated to Capital Medical University from November 2018 to February 2023 were randomly divided into a treatment group and a control group,with 54 cases in each group.The control group was given metoprolol,while the treatment group was additionally given Shensong Yangxin Capsule based on the control group.After 5 days of treatment,the cardiac function indicators,the levels of N-terminal pro B-type natriuretic peptide(NT-proBNP),6-min walk distance and the inflammatory factors,the TCM syn-drome scores of the two groups before and after treatment and the clinical efficacy were calculated.Results(1)Cardiac function level:The parameters of cardiac function in both groups were significantly improved compared with those before treatment,and the effect of the treatment group was more significant than that of the control group(P＜0.05).(2)Markers of cardiac function:After medication,the NT-proBNP of both groups decreased significantly and the 6-min walk distance increased significantly(P＜0.05).Compared with the control group,the treatment group had more significant treatment effects(P＜0.05).(3)Serum in-flammatory factors:After 5 days of treatment,the levels of CRP,IL-10 and TNF-α in the serum were significantly reduced,and the reduction effect of the treatment group was more significant than that of the control group(P＜0.05).(4)TCM syndrome score:After treatment,the scores of various items of TCM syndrome(shortness of breath,fatigue,palpitations,dyspnea,edema)in both groups were significantly reduced,and the reduction effect of the treatment group was more significant than that of the control group(P＜0.05).(5)Total effective rate:After 5 days of treatment,the clinical effective rate of the treatment group was 94.44％,significantly higher than that of the control group(79.63％),with statistical significance(P＜0.05).(6)Quality of life:After medication,the quality of life of both groups improved significantly,and compared with that of the control group,the score of the treatment group was higher(P＜0.05).Conclusion Shensong Yangxin Capsule can effectively improve the cardiac function of patients with chronic heart failure,reduce the levels of inflammatory factors,improve the clinical symptoms and quality of life of patients,and has good clinical efficacy and few adverse reactions.It is worthy of applying to the clinical treatment of chronic heart failure.
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