Effect of Modified Danzhi Xiaoyao Powder(加味丹栀逍遥散)Combined with"Soothing Liver and Regulating Spirit"Acupuncture on Cognitive Function and Prognosis of Patients with Migraine Accompanied by Depression and Anxiety Disorder
Objective To investigate the effects of Modified Danzhi Xiaoyao Powder(加味丹栀逍遥散)combined with"soothing liver and regulating spirit"acupuncture on cognitive function and prognosis of patients with migraine accompanied by depression and anxiety disorder.Methods A total of 120 patients with migraine with depression and anxiety disorder admitted to the hospital from January 2020 to January 2023 were selected as research objects.By simple random number table,they were di-vided into study group and control group with 60 cases in each group.The patients in the control group were given"soothing liver and regulating spirit"acupuncture treatment.The headache symptom scores of the two groups were compared before and after treatment.The depressive and anxiety conditions of the two groups were evaluated by Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA).The cognitive function of the patients was evaluated by Wisconsin card classification Test(WCST).The average blood flow velocities of bilateral anterior cerebral artery(ACA),posterior cerebral artery(PC A),middle cerebral artery(MC A),vertebral artery(VA)and basilar artery(BA)were measured by transcranial Doppler ultrasound(TCD)before and after treatment.Results After treatment,headache severity,attack frequency,duration,concomitant symptom score and total score of the two groups were significantly lower than those before treatment,and those of the study group were significantly lower than those of the control group(P＜0.05).After treatment,HAMA and HAMD scores of the two groups were significantly lower than those before treatment,and scores of the study group were significantly lower than those of the control group(P＜0.05).The proportion of patients with sustained response,persistent error and total error in the study group after treatment was significantly lower than that in the control group(P＜0.05).The average blood flow velocities of MCA,ACA and PCA in the two groups after treatment were lower than those before treatment,and the velocities of the study group were significantly lower than those in the control group with statistical significance(P＜0.05).No serious adverse reactions were observed in the two groups during treatment.Conclusion Modified Danzhi Xiaoyao Powder combined with"soothing liver and regulating spirit"acupuncture treatment of migraine with depression and anxiety disorder has a significant effect.The treatment can significantly improve the conditions of depression and anxiety and cognitive function and effectively reduce the average speed of arterial blood flow with high safety.It is suitable for promotion and application.
Modified Danzhi Xiaoyao Powder(加味丹栀逍遥散)soothing liver and regulating spiritmigrainedepression and anxiety disordercognitive function
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