Clinical Observation on Treatment of Chemotherapy Related Anemia in Advanced Non-Small Cell Lung Cancer with Sanjiao Buxue Ointment(三胶补血膏)
Objective To observe the clinical efficacy of Sanjiao Buxue Ointment(三胶补血膏)in the treatment of chemother-apy-related anemia in advanced non-small cell lung cancer.Methods In this study,a prospective,randomized,single-blind and controlled study was adopted.A total of 75 patients were included and randomly divided into three groups.Sanjiao Buxue Ointment group was given Sanjiao Buxue Ointment.Erythropoietin(EPO)group was given the EPO.The combination group was given Sanjiao Buxue Ointment and EPO.Twenty-one days was a course of treatment,a total of 3 courses of treatment were ob-served,and hematological indicators(red blood cells,hemoglobin,hematocrit),TCM syndrome scores and Karnofsky(KPS)scores were observed.Results Seventy-one cases were finally completed,and there were statistical differences in red blood cells,hemo-globin,hematocrit,TCM syndrome scores and KPS scores before and after treatment in the three groups(P=0.006 7;P=0.0258;P=0.003 1;P＜0.05;P=0.039).There were statistical differences(P＜0.05)in the above indexes among the three groups after treatment(P＜0.05).Taking the EPO group as the control group,there were statistical differences in hemoglobin,hemato-crit,TCM symptom scores and KPS scores between the Sanjiao Buxue Ointment group and the EPO group,and between the combi-nation group and the EPO group(P＜0.05).No serious adverse reactions were seen in the three groups,and there was 1 throm-botic event in the EPO group,and no adverse reactions were seen in the other two groups.Conclusion Sanjiao Buxue Ointment has a reliable clinical curative effect in the treatment of non-small cell lung cancer chemotherapy-related anemia,and can also improve TCM syndromes and quality of life.It can be used as a supplementary treatment for EPO in clinical practice,and it is worthy of further clinical promotion.
万方数据
维普
