Research Progress on Pharmacological Mechanisms of Danshen(Salviae Miltiorrhizae Radix Et Rhizoma)and Its Active Ingredients on Cardiovascular System
Danshen(Salviae Miltiorrhizae Radix Et Rhizoma),a traditional Chinese medicinal herb,has always been widely used in medical practice due to its excellent effects of promoting blood circulation,removing blood stasis,unblocking meridians,relieving pain,clearing the heart and removing troubles,especially in the cardiovascular system.Modern research has found that Danshen(Salviae Miltiorrhizae Radix Et Rhizoma)and its active ingredients have various effects such as anticoagulation,lipid-lowering,antithrombotic,anti-inflammatory and antioxidant stress,hypotension,protection of myocardial cells,reduction of myo-cardial cell apoptosis rate,protection of blood vessels and promotion of vascular dilation,improvement of mitochondrial dysfunction and microcirculation,prevention and treatment of ventricular hypertrophy,making it have good preventive and therapeutic effects on cardiovascular system diseases.This article reviewed the content of Danshen(Salviae Miltiorrhizae Radix Et Rhizoma)and its effective active ingredients from anti atherosclerosis,protection of myocardial cells,protection of blood vessels,improvement of my-ocardial ischemia and ischemia-reperfusion injury,prevention and treatment of hypertension and ventricular hypertrophy,so as to provide reference for the application and research of Danshen(Salviae Miltiorrhizae Radix Et Rhizoma)in cardiovascular disea-ses.
Danshen(Salviae Miltiorrhizae Radix Et Rhizoma)cardiovascular systempharmacological mechanism
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