Research Progress on Chemical Constituents,Pharmacological Effects and Clinical Application of Classic Prescription on Siwu Decoction(四物汤)and Predictive Analysis on Its Q-Markers
Siwu Decoction(四物汤)is a classic prescription for nourishing blood and replenishing blood from The Secret Formulary for Traumatology and Fracture Taught by Immortal by Taoist Lin in the Tang Dynasty,and it has the pharmacological effects of promoting bone marrow hematopoiesis,promoting erythropoiesis,repairing liver injury,estrogen-like effect,antioxida-tion,enhancing the ability of memory and study,improving metabolism and estrogen.It is commonly used in clinical treatment of anemia,gynecological diseases,orthopedic diseases,adjuvant treatment of tumors and other diseases.The research progress of chemical composition,pharmacological action and clinical application of Siwu Decoction in recent years were summarized,and the quality Marker(Q-Marker)of Siwu Decoction was analyzed according to the five principles of quality Markers.It was indicated that paeoniflorin,albiflorin,benzoylpaeoniflorin,tetramethylpyrazine,ferulic acid,senkyunolide Ⅰ,ligustilide,catalpol,5-hydroxy-methylfurfural and verbascoside can be selected as Q-Markers of Siwu Decoction.These Q-Markers components can be select-ed as indicators to control the quality of Siwu Decoction preparation.
Siwu Decoction(四物汤)quality Markerchemical compositionpharmacological actionclinical applicationquality control
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