基于脑肠轴理论的中药及干细胞诊疗帕金森病研究进展
Research Progress of Traditional Chinese Medicine and Stem Cells in Diagnosis and Treatment of Parkinson's Disease Based on Brain-Gut Axis Theory
高晨 1孙世标 1王绍娜 1应春苗 1刘飞祥 2张运克3
作者信息
- 1. 河南中医药大学,河南郑州 450046
- 2. 河南中医药大学第一附属医院,河南郑州 450000
- 3. 河南中医药大学,河南郑州 450046;河南中医药大学第一附属医院,河南郑州 450000
- 折叠
摘要
帕金森病(Parkinson's disease,PD)发病机制复杂,目前尚无治愈方法.脑肠轴是帕金森病的诊疗方向之一.中药与干细胞对帕金森病脑肠轴途径均有明确疗效,中药还可进一步调控干细胞增殖与分化.对于帕金森病脑肠轴方向的诊疗进行综述,探讨中药及干细胞疗法,并对中药调控干细胞通过脑肠轴治疗帕金森病的潜力进行探讨.
Abstract
The pathogenesis of Parkinson's disease is complex and there is no cure at present.The brain-gut axis is one of the diagnosis and treatment directions of Parkinson's disease.Both traditional Chinese medicine and stem cells have clear thera-peutic effects on brain-gut axis pathway in Parkinson's disease,and traditional Chinese medicine can further regulate the prolifer-ation and differentiation of stem cells.This article reviewed the diagnosis and treatment of Parkinson's disease along the brain-gut axis,discussed traditional Chinese medicine and stem cell therapy,and reviewed the potential of traditional Chinese medicine regulating stem cells in the treatment of Parkinson's disease through brain-gut axis.
关键词
帕金森病/脑肠轴/中药/干细胞/作用机制Key words
Parkinson's disease/brain-gut axis/traditional Chinese medicine/stem cells/mechanism of action引用本文复制引用
基金项目
国家自然科学基金项目(81974564)
国家自然科学基金项目(82104730)
中原英才计划—科技创新领军人才项目(224200510027)
出版年
2024
NETL
NSTL
万方数据