首页|个体化中医证候积分与传统中医证候积分在中医临床疗效评价中的应用对比研究

个体化中医证候积分与传统中医证候积分在中医临床疗效评价中的应用对比研究

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目的 评价个体化中医证候积分在中医临床疗效评价中的优势。方法 在中药干预双心疾病的临床试验中,分别使用个体化中医证候积分和传统中医证候积分,对患者主观症状进行疗效评价。结果 在评价准确性上,两种评价方法整体疗效相似,但分别计算两种评价方法与实际主观感受的符合率,则个体化中医证候积分明显高于传统中医证候积分,差异有统计学意义(P<0。05);在评价全面性上,传统中医证候积分中仅包含7个固定症状,而个体化中医证候积分中出现了 74个症状,几乎没有症状群完全相同的患者,两组出现频率均>30次的症状有10个,均与肝郁气滞证及其变证相关,且单个症状疗效试验组优于对照组,差异有统计学意义(P<0。05)。结论 与传统中医证候积分相比,个体化中医证候积分能够更加准确、全面地反映中医药干预前后患者主观感受的变化。
Comparative Study of Applications of Individualized Traditional Chinese Medicine Syndrome Score and Traditional Chinese Medicine Syndrome Score in Evaluation of Clinical Efficacy of Traditional Chinese Medicine
Objective To evaluate the advantages of individualized traditional Chinese medicine(TCM)syndrome score in the clinical efficacy evaluation of TCM.Methods In clinical trials of TCM intervention in double heart disease,individualized TCM syndrome scores and traditional TCM syndrome scores were used to evaluate the efficacy of subjective symptoms in patients.Re-sults In terms of accuracy of evaluation,the overall efficacy of the two evaluation methods was similar.However,when calculating the coincidence rate between the two evaluation methods and actual subjective feelings,the individualized TCM syndrome score was significantly higher than the traditional TCM syndrome score(P<0.05).In terms of comprehensiveness of evaluation,tradi-tional TCM syndrome scores only included 7 symptoms,while individualized TCM syndrome scores showed 74 symptoms,with al-most no patients with identical symptom groups.There were 10 symptoms with a frequency of more than 30 times in both groups,which were related to liver depression and Qi stagnation syndrome and its derived syndrome,moreover,the curative effect of single symptom in the experimental group was better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with traditional TCM syndrome scores,individualized TCM syndrome scores can more accurately and comprehensively reflect the changes in subjective feelings of patients before and after treatment.

clinical efficacy evaluationtraditional Chinese medicineindividualizationsyndrome score

肖蕾、欧洋、陈智慧、王建华、李京、姜钧文、闵冬雨

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辽宁中医药大学附属医院,辽宁沈阳 110032

辽宁中医药大学辽宁省中医药科学院,辽宁沈阳 110847

辽宁中医药大学中医学院,辽宁沈阳 110847

临床疗效评价 中医 个体化 证候积分

国家自然科学基金青年科学基金项目

81603504

2024

中华中医药学刊
中华中医药学会 ,辽宁中医药大学

中华中医药学刊

CSTPCD北大核心
影响因子:1.007
ISSN:1673-7717
年,卷(期):2024.42(8)