Osteoporosis(OP)is a common bone metabolic disease characterized by reduced bone mass,changes in bone mi-crostructure and susceptibility to fractures.At present,western medicine treatment often causes different degrees of adverse reac-tions.Traditional Chinese medicine has certain advantages and characteristics in the treatment of OP.Guided by the theory of traditional Chinese medicine"kidney governing bone marrow",kidney-tonifying Chinese drugs are often used in clinical treat-ment of OP,and the effect is significant.Mohanlian(Ecliptae Herba)is a traditional Chinese drug for nourishing liver and kid-ney.Recent studies shows that Mohanlian(Ecliptae Herba)and its main component wedelolactone has good anti-osteoporosis effects.In this paper,the bone formation,bone resorption effects and potential molecular mechanisms of Mohanlian(Ecliptae Her-ba)and wedelolactone in the prevention and treatment of OP were reviewed,aiming to provide a reference for the clinical applica-tion and development of Mohanlian(Ecliptae Herba)and wedelolactone.
维普
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