A Multi-Centered Clinical Study pf Xuanfei Zhisou Mixture(宣肺止嗽合剂)for Cough(Wind Evil Invading Lung Syndrome)Caused by COVID-19
Objective To evaluate the clinical efficacy of Xuanfei Zhisou Mixture(宣肺止嗽合剂)for cough(wind evil inva-ding lung syndrome)caused by corona virus disease 2019(COVID-19).Methods A multi-center,prospective,parallel con-trolled methods control method was used.The COVID-19 patients with cough(wind evil invading lung syndrome)were enrolled and divided into treatment group and control group.The control group received routine treatment for COVID-19 and the treat-ment group received Xuanfei Zhisou Mixture additionally for 7 days.The cough visual analogue scale(VAS),cough relief and disappearance and safety were compared.Results A total of 154 subjects were included in this study,with 116 cases in treatment group and 38 cases in control group.After 7-day treatment,when compared with those before treatment,cough VAS score de-creased in both groups,and the score in the treatment group decreased greatly than that in the control group(P＜0.01).Com-pared with those in the control group,the cough relief rate and disappearance rate were higher,and the median time of cough relief was lower.No adverse reactions occurred during the research process.Conclusion Xuanfei Zhisou Mixture combined with usual treatment could safely and effectively alleviate clinical symptoms of cough(wind evil invading lung syndrome)caused by COVID-19.
万方数据
维普
