Progress on Role and Mechanism of Hongqi(Hedysari Radix)in Fibrotic Diseases
Fibrosis disease is an organ sclerosing disease with complex mechanisms,which can occur in different organs and seriously affect the physiological function of organs.At present,the prevention and treatment methods of fibrotic diseases are still very limited.In-depth interpretation of its pathogenesis and search for more effective treatment methods are the focus of research in this field.Hongqi(Hedysari Radix)is a genuine medicinal herb in Gansu Province with a long history of drug use.Hedysari polysaccharide and Hedysari flavonoids have been found to have anti-fibrosis effects,but there is no literature to summarize the role and mechanism of Hongqi(Hedysari Radix)in fibrotic diseases.This article searched the relevant literature of Hongqi(Hedysari Radix)in the treatment of fibrosis diseases in the past 15 years,and summarized the main active ingredients,anti-fibrosis effects and molecular mechanisms of Hongqi(Hedysari Radix)in the treatment of fibrosis diseases,in order to provide a reference for the prevention and treatment of fibrosis diseases with traditional Chinese medicine and a basis for the clinical appli-cation and further basic research of Hongqi(Hedysari Radix).