Based on the theory of infertility caused by phlegm-dampness in ancient traditional Chinese medicine,the rela-tionship between phlegm-dampness and polycystic ovary syndrome was discussed,and the pathogenesis of polycystic ovary syn-drome was elaborated from the perspective of traditional Chinese and western medicine.It is believed that the production of"phlegm of the cyst"is the characteristic manifestation of polycystic ovary formation,and the obstruction of the cell palace by phlegm and dampness is the key to the pathogenesis of polycystic ovary syndrome.Phlegm and dampness can cause polycystic changes of ovary and abnormal regulation of hypothalamic-pituitary-ovarian axis,resulting in hormone metabolism disorder,glu-colipid abnormality,oxidative stress and iron death.The above mechanisms interact with each other,and then affect the reproduc-tive function of the cytocytosis and the development of follicles,which eventually lead to the occurrence of polycystic ovary syn-drome.
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