Research Progress of Eye Acupuncture Against Cerebralischemia-Reperfusion Injury from Autophagy Mechanism
Autophagy is a classical cell death pathway that is activated under stress conditions such as ischemia,hypoxia and nutrient deprivation.Moderate autophagy removes damaged intracellular organelles and misfolded proteins,while autophagy ex-ceeding the tolerance of the cell results in cell death,and autophagy plays an important role in cell survival,differentiation,devel-opment and homeostasis of the internal environment.Eye acupuncture can improve cerebral ischemia reperfusion injury(CIRI)by regulating autophagy mechanism through anti-apoptosis,anti-endoplasmic reticulum stress,anti-oxidative stress and other pathways.In this paper,it searched the China Knowledge Network database,Wanfang database and NCBI database from the es-tablishment of the database to December 7,2023 for the literature on CIRI activated autophagy,and analyzed the experimental da-ta related to the prevention and treatment of CIRI by eye acupuncture,to summarize the mechanism between CIRI and autophagy and the role they play in the process of prevention and treatment of CIRI by eye acupuncture,so as to provide a basis for further scientific research and clinical promotion of the eye-acupuncture treatment.
万方数据
维普
