Clinical Observation of Danggui Sini Decoction(当归四逆汤)Combined with Governor Meridian Moxibustion in Treatment of Cold Coagulation in Heart Meridian Syndrome of Microvascular Angina Pectoris
Objective To study the curative effect of Danggui Sini Decoction(当归四逆汤)combined with governor meridian moxibustion in the treatment of cold coagulation in heart meridian syndrome of microvascular angina pectoris.Methods Eighty pa-tients with cold coagulation in heart meridian syndrome of microvascular angina pectoris diagnosed and treated in the hospital from June 2022 to December 2022 were selected as the research objects and they were divided into control group and treatment group by random number table method,with 40 cases in each group.The control group was treated with conventional western medicine,and the treatment group was treated with Danggui Sini Decoction combined with governor meridian moxibustion on the basis of the control group.After 4 weeks of treatment,the TCM syndrome scores,angina pectoris attack,treadmill exercise test and biochemi-cal indexes of the two groups were observed to evaluate the efficacy,and the occurrence of adverse reactions was recorded.Results According to the TCM syndrome scores,the total effective rate of the treatment group was 95.00％(38/40),which was signifi-cantly higher than that(80.00％,32/40)of the control group(P＜0.05).After treatment,the frequency of angina pectoris at-tack,duration of each attack and pain in two groups were significantly decreased(P＜0.05),and the pain in the treatment group was significantly lower than that in the control group(P＜0.05).There was no significant difference in the indexes of treadmill exercise test between the two groups before treatment(P＞0.05).After treatment,the total exercise time and ST segment depres-sion 0.1 mV time of the two groups were significantly prolonged(P＜0.05),and the ST segment depression amplitude was de-creased(P＜0.05),and the above indexes of the treatment group were significantly better than those of the control group(P＜0.05).There was no significant difference in hypersensitive C-reactive protein(hs-CRP)or lipoprotein-associated phospho-lipase A2(Lp-PLA2)between the two groups before treatment(P＞0.05).After treatment,the levels of hs-CRP and Lp-PLA2 in the two groups were significantly decreased(P＜0.05),and the levels in the treatment group were significantly lower than those in the control group(P＜0.05).The incidence of adverse reactions in the treatment group and the control group was 7.50％(3/40)and 12.50％(5/40),and there was no significant difference between the two groups(P＞0.05).Conclusion The clinical effect of Danggui Sini Decoction combined with governor meridian moxibustion in the treatment of cold coagulation in heart meridian syndrome of microvascular angina pectoris is satisfactory.It can effectively improve the TCM syn-dromes of patients,exert analgesic and anti-inflammatory effects and has good safety.As a new treatment method,it is worthy of further discussion and application.
angina pectorismicrovascularcold coagulation in heart meridianDanggui Sini Decoction(当归四逆汤)gover-nor meridian moxibustion
万方数据
维普
