Research Progress on Effects of Processing for Pharmacological Activities and Chemical Constituents of Cangzhu(Rhizoma Atractylodes)
The aim of Cangzhu(Rhizoma Atractylodes)is to reduce dryness and increase efficiency.There are obvious differences in pharmacological activity and chemical composition between the raw product and the processed product.Raw prod-ucts have the functions of regulating gastrointestinal motility,promoting food digestion and absorption,regulating the metabolism of water and salt,affecting intestinal flora structure,neurologically regulating gastrointestinal motility,diuresis,anti-tumor and so on.But the toxic and side effects of the processed products were weakened,the effects of strengthening spleen,protecting liver and reducing enzymes were enhanced,and the activities of brightening eyesight,drying dampness,removing Bi syndrome and anti-bacterial and antiviral activities were decreased.The change of drug efficacy may be related to the decrease of volatile oil content of atractylodes and the obvious changes in the relative contents of main components.After processed of Cangzhu(Rhizoma Atrac-tylodes),the contents of total volatile oil,diisobutyl phthalate,Aractylodes ketone,Atractylodes alcohol,Atractylodes tin and β-Eudesmol decreased,but the contents of 5-hydroxymethylfurfural,Atractylodes inner ester Ⅰ,Atractylodes inner ester Ⅱ and At-ractylodes A increased.In addition,the processing also had a trend effect on the trace elements,such as Cr,Al,Mn,Zn,Pt,Cu,Na,Mg,Sr,Ba and Cd in Cangzhu(Rhizoma Atractylodes).The change of chemical composition after processing of Cangzhu(Rhizoma Atractylodes)is the material basis for reducing side effects and changing efficacy,and is also the researching direction for processing mechanism.
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维普
