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茱萸丸药理作用及临床应用研究进展

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茱萸丸出自北宋王怀隐等编纂的《太平圣惠方》,由黄连、吴茱萸等比配伍而成,二者苦辛通降、寒热并用,共同针对气机升降紊乱、寒温错杂的复合病机。从茱萸丸的药理作用和临床应用两个方面进行文献梳理,阐述了茱萸丸抗炎、降血脂、保护胃黏膜、抑菌、解热、增强热耐受、抗癌及解毒等作用机制,归纳了茱萸丸在临床上广泛运用于脂代谢性疾病、消化性疾患以及慢性溃疡等病种,并对其实验和临床研究提出不足与建议,以期为茱萸丸的研发提供参考。
Research Progress on Pharmacologic Effect and Clinical Application of Zhuyu Pill(茱萸丸)
Zhuyu Pill(茱萸丸)is derived from Taiping Shenghui Fang compiled by WANG Huaiyin and others in the Northern Song Dynasty.It is made of Huanglian(Coptidis Rhizoma)and Wuzhuyu(Euodiae Fructus),both of which aim at the complicated pathogenesis of the disturbance of Qi movement and the disorder of cold and heat.This article reviewed the literature from two aspects of pharmacological action and clinical application of Zhuyu Pill.This paper described the mechanism of Zhuyu Pill,such as anti-inflammation,reducing blood lipids,protecting gastric mucosa,antibacterial effect,antipyretic effect,enhancing heat tolerance,anticancer and detoxifying,and summarized its wide clinical application in lipid metabolic diseases,digestive dis-eases and chronic ulcers,and put forward some shortcomings and suggestions for improvement in experimental and clinical studies in order to provide relevant basis and support for further research and development and clinical application of Zhuyu Pill.

Zhuyu Pill(茱萸丸)pharmacological effectclinical applicationresearch progress

宋玮、张钟艺、王楷、沈涛

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成都中医药大学,四川成都 610075

茱萸丸 药理作用 临床应用 研究进展

2024

中华中医药学刊
中华中医药学会 ,辽宁中医药大学

中华中医药学刊

CSTPCD北大核心
影响因子:1.007
ISSN:1673-7717
年,卷(期):2024.42(12)