Clinical Effect of Zhizichi Decoction(栀子豉汤)Combined with Calming Mind and Tonifying Kidney Acupuncture on Insomnia(Heart-Kidney Disharmony Type)
Objective To observe the clinical effect of Zhizichi Decoction(栀子豉汤)combined with calming mind and tonify-ing kidney acupuncture on insomnia(heart-kidney disharmony type).Methods A total of 110 patients with insomnia(heart-kidney disharmony type)admitted to the Department of Traditional Chinese Medicine of Shanxi People's Hospital from February 2021 to March 2023 were divided into control group and observation group by random number table method,with 55 cases in each group.The patients in the control group were treated with dexzopicron tablet,and those in the observation group were treated with dexzopicron tablet combined with Zhizichi Decoction and calming mind and tonifying kidney acupuncture.During the treatment,2 patients fell off in the control group and 3 patients fell off in the observation group.The data of each group was compared,inclu-ding efficacy,TCM symptom scores(difficulty falling asleep,restlessness and insomnia,palpitations and dreams,hot flashes and night sweats,five heart restlessness,dizziness and tinnitus,etc),polysomnography(PSG)indicators,the scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS),Pittsburgh sleep quality index(PSQI),mini-mental state examination(MMSE)and short form 36 questionnaire(SF-36),and adverse reactions.Results The total effective rates of the observation group and the control group were 96.15％and 83.02％,respectively,and the total effective rate of observation group was signifi-cantly higher(P＜0.05).Before treatment,TCM syndrome scores(difficulty falling asleep,restlessness and insomnia,palpitations and dreams,hot flashes and night sweats,five heart restlessness,dizziness and tinnitus,etc),PSG related indicators(total sleep duration,wake duration,sleep latency and sleep efficiency),SAS score,SDS score,PSQI score,MMSE score and SF-36 score were not significant between the two groups(P＞0.05).After treatment,TCM syndrome score(difficulty falling asleep,upset in-somnia,palpitation and multiple dreams,hot flash and night sweat,five upset fever,dizziness and tinnitus,etc.),PSG related in-dexes(total sleep duration,wake duration,sleep latency and sleep efficiency),SAS score,SDS score,PSQI score,MMSE score and SF-36 score were significantly improved in all groups.After treatment,TCM syndrome score(difficulty falling asleep,upset insomnia,palpitation and multiple dreams,hot flashes and night sweats,five upset fever,dizziness and tinnitus,etc.),PSG related indexes(total sleep duration,wake duration,sleep latency and sleep efficiency),SAS score,SDS score,PSQI score,MMSE score and SF-36 score in the observation group were significantly better than those in the control group(P＜0.05).The rates of ad-verse reactions in the observation group and the control group were 1.92％and 13.21％,respectively,and the rate of adverse re-actions in the observation group was lower(P＜0.05).Conclusion Zhizichi Decoction combined with calming mind and tonifying kidney acupuncture acupuncture has good clinical effect on insomnia(heart-kidney disharmony type).The patient's clinical symptoms,psychological state and sleep quality all improved,and their cognitive function and quality of life have also been en-hanced.Additionally,there are fewer adverse reactions,making them relatively safe.
insomniaheart-kidney disharmony typeZhizichi Decoction(栀子豉汤)calming mind and tonifying kidney acupuncturecurative effectsleep qualityadverse reaction
万方数据
维普
