Application of Honghua Xiaoyao Tablet(红花逍遥片)Combined with Escitalopram in Patients with Diabetes Complicated with Burning Mouth Syndrome
Objective To evaluate the application of Honghua Xiaoyao Tablet(红花逍遥片)combined with escitalopram in di-abetes patients with burning mouth syndrome(BMS).Methods Prospective analysis was used in this study.Sixty-two cases of diabetes with BMS were selected from the hospital for examination and treatment.The patients were randomly divided into two groups according to a proportional random number table,with 31 cases in each group.Both groups received the same basic treat-ment,while the control group received escitalopram.The observation group received a combination of Honghua Xiaoyao Tablet and escitalopram.Two groups were treated continuously for 8 weeks.The efficacy was evaluated after 8 weeks of medication.The self rating anxiety scale(SAS),self rating depression scale(SDS),symptom checklist 90(SCL-90)and traditional Chinese medicine(TCM)syndromes were assessed before and 8 weeks after treatment,respectively,and the adverse reactions were recor-ded.Result The total effective rate of the control group was lower than that of the observation group,and the difference was statis-tically significant(P＜0.05).Compared with those before treatment,the SAS score,SDS score and SCL-90 score of the two groups decreased after treatment(P＜0.05).Compared with those of the control group,the SAS score,SDS score and SCL-90 score of the observation group patients after treatment were lower,and the difference was statistically significant(P＜0.05).Compared with those before treatment,the main symptom score,secondary symptom score and tongue pulse condition of the two groups decreased after treatment(P＜0.05).Compared with the control group,the observation group had lower main symptom score,secondary symptom score and tongue pulse score after treatment,and the difference was statistically significant(P＜0.05).There was no statistically significant difference in the total adverse rate between the two groups of patients(P＞0.05).Conclusion Honghua Xiaoyao Tablet combined with escitalopram has significant efficacy in the treatment of diabetes with BMS,which can re-duce negative emotions,improve TCM syndromes and has high safety.
Honghua Xiaoyao Tablet(红花逍遥片)exelopramdiabetes with BMS
万方数据
维普
