Objective To evaluate the clinical efficacy and safety of warming yang and activating blood for preventing deep vein thrombosis(DVT)after operation of gynecologic malignancy.Methods A retrospective analysis was conducted on 85 patients after operation of gynecologic malignancy in The First Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2023 to December 2023.Wenyang Fangshuan Formula group(WYFS group)included 64 cases while the low molecular weight heparin group(LMWH group)contained 21 cases according to different postoperative prevention methods.The incidence of postoperative DVT,the levels of D-Dimer(D-D)and platelet on the 1st,3rd,and 7th day after surgery were compared between the two groups.Results The incidence of postoperative DVT in the WYFS group was lower than the LMWH group(9.38%vs 19.05%),but the difference was not statistically significant(P＞0.05).The level of D-D in the WYFS group was significantly lower than the LMWH group on the 1st day after surgery(P＜0.05).The level of platelet in the WYFS group was slightly lower than the LMWH group,and there was no statistically significant difference between the two groups(P＞0.05).In terms of adverse events,the incidence of the WYFS group was lower(liver function impairment rate:12.5%vs 38.1%),and the difference was statistically significant(P＜0.05).Conclusion Wenyang Fangshuan Formula is more effective than low molecular weight heparin in preventing DVT formation after operation of gynecological malignant tumor,with fewer adverse reactions.
关键词
温阳活血法/下肢深静脉血栓/妇科恶性肿瘤/中药外治/回顾性研究
Key words
warming yang and activating blood/deep vein thrombosis/gynecologic malignancy/external treatment of traditional Chinese medicine/retrospective research
维普
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