首页|Effectiveness and safety of acupuncture in treatment of pregnancy-related symptoms:a systematic review and Meta-analysis
Effectiveness and safety of acupuncture in treatment of pregnancy-related symptoms:a systematic review and Meta-analysis
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OBJECTIVE:To systematically evaluate the efficacy and safety of acupuncture(AM)in the treatment of pregnancy-related symptoms such as acute vomiting during pregnancy.METHODS:We comprehensively searched the available literature up to November 2021,including PubMed,Embase,Cochrane Library,Chinese Biomedical Literature Database,and China National Knowledge Infrastructure Database,for randomized controlled trials(RCTs)on AM for the treatment of severe vomiting,insomnia,pharyngeal and pelvic pain,mood abnormalities,and dyspepsia during pregnancy.RESULTS:Sixteen RCTs with a cumulative sample size of 1178 cases were included.Of these,964 patients were included in the Meta-analysis.The Meta-analysis results showed that AM was more efficient than Western medicine in treating discomfort during pregnancy[odds ratio(OR)=1.19,95%confidence interval(CI)(1.11,1.28),P<0.01].AM was better than the control group in improving the visual analog scale scores[standard mean difference(SMD)=0.62,95%CI(0.53,0.71),P<0.01].AM was superior to the control group in improving Numerical Rating Scale(NRS)symptom scores[OR=7.31,95%CI(3.36,15.94),P<0.01].There was no significant difference in adverse effects between the AM and sham-AM groups and the analgesic drug group[OR=0.70,95%CI(0.39,1.28),P=0.25],but the treatment and control groups had mild adverse effects with a low incidence.CONCLUSIONS:AM is more effective than other treatments or pharmacotherapy alone in the treatment of pregnancy-related symptoms,and is relatively safe.However,the quality of the included trials was rather poor,and high-quality studies are required to confirm our findings.
acupuncturepregnancynauseavomitingsleep initiation and maintenance disorderslow back painpelvic painmood abnormalitiesMeta-analysissystematic review
LIU Tingting、LIU Tongou、LIU Mingfu
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School of Traditional Chinese Medicine Clinical Medicine,Hubei University of Traditional Chinese Medicine,Wuhan 430000,China
First Clinical College of Hubei University of Traditional Chinese Medicine,Wuhan 430000,China
Department of Acupuncture and Tuina,Affiliated Hospital of Hubei University of Traditional Chinese Medicine,Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan 430000,China
Project of Science and Technology Department of Hubei Province in 2023