首页|Revealing the scientific connotation of compatibility of Chinese medicine medica based on self-assembly technology

Revealing the scientific connotation of compatibility of Chinese medicine medica based on self-assembly technology

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Revealing the scientific connotation of compatibility of Chinese medicine medica based on self-assembly technology
Chinese materia medica(CMM)compatibility is one core content in the theory of Traditional Chinese Medicine(TCM),and elaborating the scientific connotation of CMM compatibility is of great significance to promote the modernization of TCM.Self-assembly is the combination of active ingredients into aggregates through non-covalent bonds,such as hydrogen bonding,electrostatic interactions,ionic interactions,and hydrophobic interactions.The complex properties and special structures of CMM components create the basis for self-assembly.The self-assembled materials formed after CMM compatibility is an important part of the material basis for the efficacy of TCM,which can help explain the scientific connotations of CMM compatibility.This review summarizes the self-assembly phenomenon from the perspective of drug pair combinations in recent decades and explains the scientific connotation of CMM compatibility about the material basis,pharmacodynamic changes,and mechanism of action,providing new ideas and methods for the study of TCM.

Chinese materia medica compatibilitymedicine,Chinese Traditionalself-assembly phenomenonreduce adverse reactions and increase desired effectscomponent interactionsreview

DONG Yingying、GUO Qin、GAO Yuan、WANG Huanhuan、BAI Dong

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Institute of Basic Theory of Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China

Basic Medical School,Shaanxi University of Chinese Medicine,Xianyang 712046,China

Chinese materia medica compatibility medicine,Chinese Traditional self-assembly phenomenon reduce adverse reactions and increase desired effects component interactions review

2024

中医杂志(英文版)
中国中医药学会 中国中医研究院

中医杂志(英文版)

影响因子:0.855
ISSN:0255-2922
年,卷(期):2024.44(6)