摘要
"因加而发"作为《黄帝内经》所载的发病机理之一,将新邪引动故邪致病与新故合邪致病涵盖其中.基于此,认为肺结节"结癌转化"之变实为本元亏虚的基础上,新邪诱发痰凝、气滞、血瘀、毒结等故邪,正气无力驱邪外出,久羁为患,变生癌浊,日久发为癌瘤.故临床在癌毒未成、癌毒氤氲、癌变已成3个阶段治疗的基础上,采用清、透、散、补、和、化六法,标本兼顾,将肺结节治疗窗口前移,攻邪于毒未鸱张亢盛之时,扶正于正气尚未衰败之际,延缓肺结节癌变进程,为中医防治肺结节"结癌转化"提供思路.
Abstract
As one of the pathogenic mechanisms contained in The Inner Canon of Yellow Emperor《黄帝内经》),"disease with latent pathogen induced by a new pathogen"means that the induced new pathogen resulted to a combina-tion of the latent previous pathogen and the new pathogen,which caused the disease.Based on this,it is believed that the change of"nodule-cancer transformation"of pulmonary nodules is actually based on the deficiency of original qi,and the new pathogen induces the latent pathogens like phlegm coagulation,qi stagnation,blood stasis,toxicity,so healthy qi can not drive the pathogens out,and the long-time detention generated into cancerous turbidity,and deve-loped into cancerous tumour at the end.Therefore,based on the three-stage treatment of unformed cancer,dense can-cerous toxin,and developed cancer,the clinical practice applied six methods of clearing,expelling,dissipating,toni-fying,harmonizing,and transforming,taking into account both the manifestation and root cause,moving the treat-ment window of pulmonary nodules forward,attacking the pathogens when the toxin was not yet overbearing,support-ing the healthy qi before declining,delaying the process of nodules-cancer transformation,and providing ideas for the prevention and treatment of pulmonary nodules"nodule-cancer transformation"in traditional Chinese medicine.
基金项目
国家中医药管理局中医药行业科研专项(201307006)
中国中医科学院广安门医院科研基金(2023031)