Methodology for the Development of Clinical Practice Guidelines for Chinese Patent Medicine(Part 3):Identification of Clinical Questions
The identification of clinical questions for clinical practice guidelines of Chinese patent medicine(CPM)is important for subsequent evidence retrieval,evaluation of evidence quality,formation of recommendations.This paper described a methodological proposal for the identification of clinical questions for CPM guidelines to high-light the characteristics of Chinese patent medicine and reflect its effect in specific stage of the disease.Considering four aspects,namely,the drug of Chinese patent medicine(D),the specific disease stage(S),comparison(C),and specific outcome(0),DSCO framework has been proposed to formulate the clinical questions.Multi-source infor-mation through scientific research,policy or standard documents,and clinical data are suggested for collecting clini-cal questions,and clear selection criteria should be set to finalize the clinical questions to be addressed by the guideline.In addition,the above process needs to be transparently and publicly reported in order to ensure the clarity and completeness of the guidelines.
clinical practice guidelinesChinese patent medicineclinical questionsmethodology