Clinical Study of Modified Shenqi Pill(肾气丸)Plus Tongdu Tiaoshen Acupuncture(通督调神针刺)for Neurogenic Bladder After Spinal Cord Injury of Kidney-Yang Deficiency Syndrome
Clinical Study of Modified Shenqi Pill(肾气丸)Plus Tongdu Tiaoshen Acupuncture(通督调神针刺)for Neurogenic Bladder After Spinal Cord Injury of Kidney-Yang Deficiency Syndrome
Objective To observe the clinical efficacy of modified Shenqi Pill(肾气丸)plus Tongdu Tiaoshen Acupuncture(通督调神针刺)in the treatment of neurogenic bladder after spinal cord injury of kidney-yang deficiency syndrome.Methods Forty-six patients were randomly divided into 23 cases each in the control group and the treat-ment group.Both groups were given conventional treatment,i.e.oral methylcobalamin tablets(0.5 mg each time,3 times a day)and paraplegic conventional acupuncture(once a day,6 consecutive days a week).The control group was given simple bladder function rehabilitation training on the basis of the conventional treatment;and the treatment group was given modified Shenqi Pill orally(1 dose a day,150 ml each time,taken warmly in morning and evening)and Tongdu Tiaoshen Acupuncture(once a day,6 consecutive days per week)in addition to what were given to the control group.The treatment course lasted for 4 weeks.The 24 h urination frequency,24 h urine leakage frequency,24 h single urine volume,bladder residual urine volume,international lower urinary tract symptom(LUTS)score,traditional Chinese medicine(TCM)syndrome score were compared between the two groups,and clinical effective-ness and TCM syndrome effectiveness were compared between the two groups after treatment.Results Twenty patients in each group were finally analyzed in this study.The number of 24 h urination,the number of 24 h urine leakage,bladder residual urine volume,LUTS score,and the TCM syndrome scores decreased after treatment in both groups,and the 24 h single urine volume increased(P＜0.01);and much more improvement was found of each index in the treatment group than in the control group(P＜0.05 or P＜0.01).The total clinical effectiveness and TCM syndrome effectiveness in the treatment group was 85.00％(17/20)respectively,which were statistically signif-icantly higher than 45.00％(the total clinical effectiveness,9/20)and 60.00％(TCM syndrome effectiveness,12/20)in the control group(P＜0.01).Conclusion Modified Shenqi Pill plus Tongdu Tiaoshen Acupuncture can signi-ficantly improve the clinical symptoms of neurogenic bladder patients after spinal cord injury of kidney-yang deficiency syndrome,having better effectiveness than simple bladder function rehabilitation training,and its mechanism may be related to the improvement of the injured nerve function innervating the bladder.
维普
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