摘要
总结彭培初教授分三期四阶段辨治前列腺癌的临证经验.认为前列腺癌属本虚标实证,以正气亏虚为本、癌毒蕴积为标.临证根据前列腺癌发生发展过程中的邪正盛衰状态及阴阳虚实变化分三期四阶段进行辨治.癌毒初结期(阳实阶段)以湿热瘀血蕴积、癌毒内生为关键病机,治宜解毒抗癌祛阳实;正虚毒蕴期(阴虚阶段)以肺肾阴虚、湿热瘀毒蕴积为关键病机,治宜金水相生滋肾阴为主,兼用清热利湿、活血解毒,常用自拟南北方;阳虚寒滞期(阳虚、阴实阶段)以脾肾阳虚、寒湿凝滞、瘀热毒蕴为关键病机,治宜温补脾肾散寒结,阴阳两虚、实邪阻滞者用阳和汤加减,阳虚、寒凝血瘀者用自拟温肾散结方,寒湿胶结癌毒、寒热错杂者用自拟泉安方.
Abstract
This paper summarized Professor PENG Peichu's experience in the differentiation and treatment of prostate cancer in three phases and four stages.It is considered that prostatic cancer is categorized into root deficiency and branch excess,with depletion of healthy qi as the root,and the accumulation of cancer toxin as the minifestation.Clinical diagnosis and treatment of prostatic cancer can be divided into three phases and four stages according to the exuberance and decline of pathogenic and healthy qi and the changes of deficiency and excess of yin and yang.In the initial accumulation phase of cancer toxin(yang excess stage),the key pathogenesis is the accumulation of damp-ness,heat and static blood,and internal generation of cancer toxin,and the treatment should be resolving toxins,fighting cancer and dispelling yang excess.In the phase of healthy qi deficiency and toxin accumulation(yin deficiency stage),with the lung and kidney yin deficiency,dampness,heat and static toxin accumulation as the key pathogenesis,the treatment should be centered on mutual generation between metal and water to nourish kidney yin,supplemented with the method of clearing heat and draining dampness,activating blood and resolving toxins,for which self-made Nanbei Formula(南北方)is usually used.In the phase of yang deficiency and cold stagnation(yang deficiency stage and yin excess stage),with the spleen and kidney yang deficiency,cold dampness stagnation,static heat and toxin accumulation as the key pathogenesis,the treatment should be warming and tonifying spleen and kidney to dissipate cold accumulation;for deficiency of both yin and yang,and excess pathogen obstruction,modified Yanghe Decoction(阳和汤)is recommended,while for yang deficiency,cold congealing and blood stasis,self-made Wenshen Sanjie Formula(温肾散结方)can be used,and for cold dampness binding with cancer toxin,and cold complex with heat,self-made Quanan Formula(泉安方)is advised.
基金项目
国家自然科学基金(82174451)
岳阳医院中医专科建设专项(YW2023-2024-01-04)