摘要
《素问·异法方宜论篇》提出导引适应症"痿病治宜导引",并明确导引适应症是指湿、食杂、不劳等导致的与脾和湿相关,以肢体困重、倦怠乏力为主症的病症,类似于现代医学糖脂代谢病早期代谢失衡状态.现代临床和基础研究证据表明,导引可以通过抑制炎症反应、缓解氧化应激、调节肠道菌群、调控基因表达,进而改善代谢异常状态,为导引适应症的研究提供思路.
Abstract
It has been proposed by Basic Questions On Proper Therapies for Different Diseases Geographically(《素问·异法方宜论篇》)that"wei(痿)diseases should be treated by Daoyin(导引)".Furthermore,it is clarified that the indications of Daoyin are those conditions related to spleen and dampness caused by dampness pathogen,excessive food intake and less exercise,and mainly manifested as heavy limbs,fatigue and flaccidity,which is similar to the metabolic imbalance in the early stage of glucose or lipid metabolism disorder in modern medicine.Based on modern clinical and basic research evidence,Daoyin can inhibit the response of inflammation,alleviate oxidative stress,regu-late intestinal microbiota,and modulate gene expression to improve metabolic abnormalities,and this will provide ideas for researches on the indications of Daoyin.
基金项目
省部共建中医湿证国家重点实验室专项(SZ2021ZZ08)
国家重点研发计划(2018YFC1707803)