Discussion on the Treatment of Heart Failure from the Theory of "Sweat Pore-Collaterals-Zang and Fu Organs" Based on Mitochondrial Function
Mitochondria are the main site of energy metabolism in cardiomyocytes,and at the same time mediate apoptosis and immune response,so mitochondrial dysfunction is closely related to the development of heart failure.Combined with the pathogenesis of mitochondrial dysfunction and heart failure,it is proposed that the mitochondrial function is similar to"sweat pore-collaterals-zang and fu organs",according to which the treatment of heart failure is based on the theory of"sweat pore-collaterals-zang and fu organs".It is believed that the core mechanism of heart failure is qi deficiency,and qi deficiency leads to the weakness of the sweat pore opening and closing,or even the sweat pore closure,then resulting in qi deficiency and blood stasis,collaterals stagnation fail to flourish,and qi,blood,and body fluids can not infiltrate and nourish zangfu organs,so that the heart fail to be nourished,and the dis-ease will develop.The treatment should be based on the method of boosting qi and opening sweat pore,using acridity to unblock the collaterals,and invigorating blood and draining water,with medicinal of boosting qi,invigorating blood,and draining water as treatment.
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