The Common Somatic Symptoms of Bipolar Disorder and Their Relationships with Five-State Personality and Emotional Symptoms Based on Complex Networks and Linear Regression
Objective To analyze the relationship between somatic symptoms,five-state personality and emo-tional symptoms of bipolar disorder(BD),and to provide a reference for the clinical diagnosis and treatment of BD.Methods The basic information of the BD patients was collected,and the self-administered somatic symptom questionnaire was used to investigate the somatic symptoms with a frequency of＞20％,which were scored as the so-matic symptom scores;the 24-item Hamilton Depression Scale(HAMD)was used to evaluate the patients'depressive symptoms,the Young Mania Rating Scale(YMRS)was used to evaluate the patients'manic symptoms,the Hamilton Anxiety Scale(HAMA)was used to evaluate the patients'anxiety symptoms,and Five-State Personality Test was used to evaluate the patients'five-state personality(including taiyang personality,shaoyang personality,yin-yang balance personality,shaoyin personality,and taiyin personality).Network analysis and linear regression were used to analyse the correlation between the somatic symptom scores and the five-state personality scores,HAMD scores,YMRS scores,and HAMA scores.Results There were 269 patients with BD included,and 19 somatic symptoms with a frequency of＞20％,the top three being lack of strength(152 cases,56.51％),dry mouth(137 cases,50.93％),and preference for cold drinks(112 cases,41.64％),and the somatic symptom scores were[7.0(0,10.0)]points;the YMRS scores were[3.0(0,7.5)]points;the HAMD scores were[11.0(5.0,18.0)]points;and HAMA score was[6.0(2.0,10.0)]points.Among the five-state personalities,taiyang personality[10.0(7.0,13.0)]score;shaoyang personality[10.0(7.5,13.0)]score;yin-yang balance personality[5.0(3.0,7.0)]score;shaoyin personality[13.0(10.0,16.0)]score;and taiyin personality[14.0(9.0,18.0)]score.Complex network analysis showed that BD somatic symptoms were positively correlated with taiyin personality score(r=0.23),HAMD score(r=0.21),and YMRS score(r=0.13);taiyin personality score was positively correlated with HAMD score(r=0.17)and negatively correlated with YMRS score(r=-0.03).Linear regression analyses showed that somatic symptom scores were positively correlated with HAMD score(β=0.138,P=0.003),YMRS score(β=0.128,P=0.006),and taiyin personality scores(β=0.182,P＜0.001).Conclusion Dep ression,mania,and taiyin personality are independent risk factors for somatic symptoms in patients with BD,and taiyin personality is strongly associated with somatic symptoms in patients with BD.
万方数据
维普
