Exploring the Application of Phenomics in Traditional Chinese Medicine Syndromes Studies Based on the Relationship between Phenotypes and Syndromes
By analysing the conceptual connotations of phenotype and traditional Chinese medicine(TCM)symp-toms,the relationship between TCM symptoms,phenotypes and diseases is explained.It is believed that phenotypes and TCM syndromes have certain similarities,both of which elaborate the physiological and pathological mechanisms of the human body through external manifestations,and have the temporal and spatial characteristics of both phases and wholeness,as well as focusing on the connection between the innate and the acquired.Summarising the current status of the application of phenomics technology in the studies of TCM syndromes,it is concluded that the study of the intrinsic biological mechanisms of TCM syndromes with the help of phenomics technology has achieved certain results,but there are still problems such as difficulties in matching between traditional Chinese medicine syndromes and phenotypes,the incompleteness of the existing disease phenotype system,and the inconsistency of the under-standing about"syndromes".It is proposed that in the future,large-scale clinical databases could be used to collect a wide range of TCM syndromes and phenotypes that are closely related to specific diseases.The phenomics technology could make preliminary correspondence and identification between a single syndrome and the corresponding pheno-type,and then further carry out a more accurate phenotypic detection of the composite syndromes,and finally realise the standardization and intelligence of the diagnosis of TCM syndromes with the help of the artificial intelligence tech-nology.By elaborating the modern scientific connotation of TCM syndromes from the perspective of phenotypes,we can provide scientific basis for the determination of TCM syndromes and the clarification of modern biomarkers of syn-dromes,as well as ideas for the modernisation research of TCM syndromes.