Neck Seven-Line Method Combined with Periauricular Acupuncture for 33 Patients with Sudden Hearing Loss in Non-Acute Stage:A Randomized Controlled Trial
Objective To evaluate the effectiveness and safety of neck seven-line method combined with periau-ricular acupuncture as salvage treatment for sudden hearing loss in non-acute stage.Methods Sixty-six patients with non-acute stage of sudden hearing loss with a disease duration of 15-90 days were randomly divided into 33 cases each in treatment group and control group.The treatment group was given neck seven-line method combined with acu-puncture at periauricular points;the control group used sham acupuncture and sham electroacupuncture at the same points.Both groups were treated 3 times a week for 6 weeks.The pure tone average hearing threshold of impaired frequencies were examined before treatment,after treatment finish and at follow-up(week 10),and the difference between pure tone average hearing threshold of impaired frequencies before and after treatment was calculated;calculate the proportion of patients with≥10 dB improvement in pure tone average hearing threshold of impaired frequency after treatment and at follow-up;compare the patients'Tinnitus Evaluation Scale(TEQ)scores,Chinese Medicine Quality of Life Assessment Scale(CQ-11D)health utility values and the difference between before and after treatment,and re-cord the occurrence of adverse events.Results The pure tone average of impaired frequency in the treatment group were(50.57±18.07)dB and(47.70±17.42)dB at post-treatment and follow-up respectively,and(54.38±21.77)dB and(53.36±20.99)dB in the control group at post-treatment and follow-up.Compared with the pre-treatment pe-riod,the pure tone average hearing threshold of impaired frequency in the two groups significantly decreased(P＜0.05)at post-treatment and follow-up.The difference of pure tone average hearing threshold of impaired frequency in the treatment group after treatment and at the follow-up visit compared to that before treatment was lower than those in the control group(P＜0.05).After treatment,13 patients(39.39％)in the treatment group and 10 patients(30.30％)in the control group showed improvement of≥10 dB in pure tone average hearing threshold of impaired frequency;at the follow-up visit,18 patients(54.55％)in the treatment group and 10 patients(30.30％)in the control group showed improvement of ≥10 dB in the pure tone average hearing threshold of impaired frequency,and there was no statistical significance for comparison between groups at the time of post-treatment and follow-up(P＞0.05).The TEQ score of the treatment group significantly lower than that before treatment(P＜0.05);the TEQ score of the treat-ment group and the difference between before and after treatment significantly lower than that of the control group(P＜0.05).The difference in CQ-11D health utility values and the difference between before and after treatment were not statistically significant between the two groups(P＞0.05).Eight cases of acupuncture-related adverse events occurred among 66 patients,including subcutaneous haematomas after needling,severe pain during needling and needle fainting,which disappeared after symptomatic treatment and did not affect the following treatment.Conclusion Neck seven-line method combined with periauricular acupuncture could be used as salvage treatment for sudden hearing loss in non-acute stage to improve the pure tone average hearing threshold of impaired frequency,alleviate tinnitus,with safety.
sudden hearing losselectroacupuncturepure tone average hearing thresholdtinnitusrandomized controlled trialneck seven-line method
万方数据
维普
