Midnight-Noon Ebb-Low Acupuncture by Hour-Prescription of Points Combined with Western Medicine for Parkinson's Disease with Restless Legs Syndrome:A Randomized Controlled Trial
Objective To observe the clinical effectiveness of midnight-noon ebb-low acupuncture by hour-prescription of points combined with western medicine for patients of Parkinson's disease with restless legs syndrome.Methods Sixty cases of Parkinson's disease with restless legs syndrome were divided into a control group and a treat-ment group randomly,with 30 cases in each group.The control group was given conventional western medicine treat-ment,and the treatment group was given the treatment of the control group with midnight-noon ebb-low acupuncture by hour-prescription of points based on Daling(PC7),Zhongzhu(TE3),Yanglingquan(GB34),Zusanli(ST36),and Sanyinjiao(SP 6)with perpendicular insertion,and Baihui(GV 20)with oblique insertion to the back,all of them used the manipulation of neutral reinforcement and reduction;Dudu(SP 2)and Taibai(SP 3)acupoints were inserted in accordance with the direction of the meridian travelling when the patients inhaled,and the needle was removed when exhaled;the time of acupuncture manipulation selected as Si time(9 AM-11 AM),the needle stay for 30 mins each time,once a day,5 times a week,a total of 4 weeks of treatment.The international restless legs severity scale(IRLSS),Pittsburgh sleep quality index(PSQI),Parkinson's disease quality of life questionnaire(PDQ-39),and the International Movement Disorder Society unified Parkinson's disease rating scale part Ⅰ(MDS-UPDRS Ⅰ)were compared before and after the treatment,and the clinical effectiveness of the two groups were compared after the treat-ment.Results IRLSS scores,PSQI scores,PDQ-39 scores and MDS-UPDRS Ⅰ scores decreased in both groups after treatment compared to those before treatment(P＜0.05 or P＜0.01).After treatment,the total effective rate in the treatment group(83.3％,25/30)was higher than that in the control group(60％,18/30)(P＜0.05).Conclusion Adding midnight-noon ebb-low acupuncture with hour-prescription of points on conventional western medicine treat-ment for Parkinson's disease with restless legs syndrome can significantly improve patients'clinical symptoms,sleep quality,quality of life,and enhance clinical effectiveness.
Parkinson's disease(PD)restless legs syndromeacupuncturemidnight-noon ebb-lowhour-prescription of pointsrandomized controlled trial
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