Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment
It is proposed that the disease mechanism evolution of systemic lupus erythematosus can be summa-rized into four stages:initial invasion and latency,the pathogenesis remains concealing;latent toxin accumulation,the disease gradually becomes apparent;active toxin begins damaging,the disease manifests aggressively;damage re-sulting to deficiency,the disease course prolonged.Based on the stages of latent toxin evolution,the syndrome differ-entiation and treatment of systemic lupus erythematosus can be summarized as follows:during the initial latent stage,characterized by latent dampness and heat stagnation,modified Sanren Decoction(三仁汤)should be used;in the toxin outbreak stage,marked by intense heat toxin,modified Xijiao Dihuang Decoction(犀角地黄汤)combined with modi-fied Qingwen Baidu Decoction(清瘟败毒饮)should be used;during the toxin damage stage,which presents as latent toxin damaging zang-fu organs,modified Qinghao Biejia Decoction(青蒿鳖甲汤)should be used;in the healthy qi de-ficiency stage,characterized by deficiencies of qi,blood,yin,and yang,modified Xieli Shiquan Ointment(燮理十全膏)should be used.
systemic lupus erythematosusyin-yang toxinlatent toxinevolution of disease mechanism