Clinical Evaluation of New Chinese Herbal Medicines for Syndromes:A Preliminary Study on Target Design
There are certain limitations in the current clinical evaluation methods and evaluation modes of new Chinese herbal medicines for syndromes,and there is a lack of a clinical evaluation system that meets the characteris-tics of traditional Chinese medicine(TCM).Based on the characteristics of TCM"syndrome differentiation and treat-ment"and"correspondence of formulas and syndromes",the target design model,hypothesis and its scope of applica-tion are proposed on the basis of the combination of diseases and syndromes.On the basis of fully considering the dual factors of diseases and syndromes,we distinguished the"centre of the target","middle ring"and"outer ring"through the differences of different signs and symptoms in people with same syndrome,in order to determine the degree of con-formity of the syndrome.Then,the population with same syndrome could be analysed according to the"centre of the target","middle ring"and"outer ring",so as to achieve the precise positioning of new Chinese herbal medicines for syndromes,and try to provide research ideas and methods for syndrome differentiation and treatment of TCM and pre-cise intervention.
new Chinese herbal medicinessyndromesclinical evaluationtarget designcombination of diseases and syndromescorrespondence of formulas and syndromes