Governer Vessel(督脉)Moxibustion for Regulating and Replenishing Spleen and Kidney Yang Deficiency in Patients with Amyotrophic Lateral Sclerosis:22 Cases Observation
Objective To observe the clinical effect and safety of Governer Vessel(督脉)moxibustion on amyo-trophic lateral sclerosis(ALS)patients with spleen and kidney yang deficiency.Methods Forty-four ALS patients with spleen and kidney yang deficiency were finally enrolled,and they were divided into 22 cases each in the treat-ment group and the control group.The control group was treated with oral riluzole tablets,intravenous drip of edara-vone injection,oral Qiu's Wenshen Zhiwei Decoction(裘氏温肾止痿汤),and conventional rehabilitation nursing,while the treatment group was additionally given Governer Vessel moxibustion based on the control group.The moxi-bustion treatment was applied once a week for a course of 2 weeks.Both groups were treated for 3 months.The scores of amyotrophic lateral sclerosis symptom score in integrative treatments(ALS-SSIT)for evaluating therapeutic effect of traditional Chinese medicine and amyotrophic lateral sclerosis functional rating scale-revised(ALSFRS-R)were assessed before treatment and after 1 month,2 months and 3 months treatment,and the occurrence of adverse reac-tions in both groups was observed.Results The treatment group showed a significant decrease in oropharyngeal function score,muscle function score,and non-motor symptom score,and an increase in ALSFRS-R scale scores after 1,2,and 3 months of treatment(P＜0.05).The scores of oropharyngeal function and muscle function in the control group increased,while the ALSFRS-R score decreased after 1,2 and 3 months of treatment,and the non-motor symptom score decreased after 2 and 3 months of treatment(P＜0.05).The scores of muscle function and non-motor symptoms in the treatment group were lower than those in the control group after 1 month of treatment;the scores of oropharyngeal function,muscle function and non-motor symptoms were lower than those in the control group,while the ALSFRS-R score was higher after 2 months and 3 months of treatment(P＜0.05).Constipation(3 cases),skin itching(2 cases),skin rash(1 case),and dry mouth and tongue(1 case)occurred in the treatment group,while there were 2,1,2,and 2 cases of each adverse reaction in the control group,respectively,with no sig-nificant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Du mai moxibustion on the basis of integrated Chinese and western medication and conventional rehabilitation care can help improve some clinical symptoms of ALS patients with spleen-kidney yang deficiency,and has good safety.
amyotrophic lateral sclerosisGoverner Vessel(督脉)moxibustionspleen-kidney yang deficiencyamyotrophic lateral sclerosis symptom score in integrative treatments(ALS-SSIT)for evaluating therapeutic effect of traditional Chinese medicineamyotrophic lateral
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维普
