Standardized gastroscopy screening makes the diagnosis of precancerous lesions of gastric cancer(PLGC)clearer.Correa evolution is the key to gastritis-cancer transformation,suggesting that PLGC is the core of the body's transformation from normal to cancer.Based on the"five-view differentiation and treatment"system for malig-nant tumors,we explored the establishment of a new system for preventing and treating malignant transformation of benign and inflammatory lesions from five dimensions,including pre-disease view,time-space view,core view,symp-toms view and precision view.(a)pre-disease view:early intervention to intercept inflammation-cancer transforma-tion;(b)time-space view:following the time-space framework as the disease progresses;(c)core view:focusing on the core pathogenesis of inflammation-cancer transformation.In terms of different stages,qi deficiency and stagnation are mainly manifested in the early stage,which can be treated by invigorating qi and resolving constraint;in the middle stage,yin turbidity is blocked internally,and it can be treated by warming yang and removing turbidity;in the cancerous stage,cancer toxin are blocked,for which the anti-cancer,toxins-resolving and stasis-dissolving method is suggested.In terms of the location of the disease,it is suggested to relieve disease in the upper body by rectifying qi and dissolving phlegm with emetic therapy(vomit induction);for the disease in the middle,it it suggested to nourish yin and clear heat by elimination method;pathogen in the lower requires dredging method by moving qi and dissipat-ing cold;(d)symptoms view:using herbal pairs to deal with the main symptoms;(e)precision view:enriching targets to prevent and control cancer directionally.
关键词
胃癌前病变/炎-癌转化/Correa演变
Key words
precancerous lesions of gastric cancer/inflammation-cancer transformation/Correa evolution