Discussion on the Scientific Connotation of Disease Mechanism of Stasis and Toxin Interaction of Liver Cancer based on Neutrophil Extracellular Traps
This article is to illustrate the connection between neutrophil extracellular traps(NETs)and stasis-toxin interactions during the development of liver cancer,and to provide ideas for the prevention and treatment of liver cancer.It is believed that the mechanism of tumor-related thrombosis formation caused by NETs is closely related to"stasis"in traditional Chinese medicine(TCM),and the continuous maintenance or enhancement of tumor microenvi-ronment by NETs is closely related to"toxin"in TCM;the strong coagulation-promoting effect of NETs makes the lo-cal microenvironment,which can be regarded as the toxin caused by blood stasis;the changes of tumor microenviron-ment induced by NETs further induced platelet aggregation,which may present a state of stasis caused by toxin;the pathological changes of liver cancer caused by NETs can be regarded as the microscopic manifestation of the mecha-nism of stasis-toxin interaction of liver cancer.
liver cancerstasis and toxin interactionneutrophil extracellular trapsdisease mechanism
NETL
NSTL
万方数据
