With increasing aging,cognitive impairment in elderly coronary heart disease is a"disease group"with high morbidity and mortality in the senior population,which seriously affects the health and quality of life of the elderly.This paper takes the"cardio-cerebral circuit"as the basis of co-morbidity,and under the guidance of the cardio-cerebral homoeopathy,based on the temporal sequential characteristics of the evolution of the disease mecha-nism of cognitive impairment in elderly coronary heart disease,we construct a"disease-syndrome-phase"prevention and treatment strategy based on the time-sequential characteristics of the pathogenesis of the disease mechanism of"deficiency-blood stasis-toxicity",from the perspective of pathogenicity of the disease mechanism in time-phase and the spatial multidimensionality of cardio-cerebral homoeopathy.The prevention and treatment strategy of the"disease-syndrome-phase"is constructed from the perspective of the temporal phase of the disease mechanism and the multidi-mensionality of the space of cardio-cerebral homoeopathy.In the earlier stage,"kidney deficiency and brain empti-ness are the foundation",in the attack stage,"turbid stasis and brain injury are the key",and in the progression stage,"toxicity and brain damage are the changes".It is emphasized that replenishing the deficiency and benefiting the kidneys to restore the smooth flow of collaterals,eliminating blood stasis and removing turbidity to promote the enrichment of blood,and detoxifying and clearing the heart to tranquilize the spirit and benefit the brain,the spatio-temporal thinking of cognitive impairment of coronary heart disease in the elderly is initially constructed with the spa-tial dimension to identify the location of the disease,and the temporal dimension to determine the stage of the disease,which will provide a theoretical basis for the spatiotemporal diagnostic and treatments for the heart and brain co-morbidities of TCM.
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