首页|亚临界水提取灵芝多糖的工艺研究

亚临界水提取灵芝多糖的工艺研究

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考察了亚临界水提取灵芝多糖的最佳试验条件.通过单因素和正交试验,优选出最佳提取条件为:亚临界水温度150℃,料液比(g/mL) 1:12,浸提时间为5 min,提取压力5 MPa.此工艺条件下灵芝多糖的得率可达2.15%.与传统的热水浸提法比较,亚临界水提法可明显缩短提取时间和降低成本,且得率更高.
SUBCRITICAL WATER EXTRACTION OF POLYSACCHARIDE FROM GANODERMA LUCIDUM
Ganoderma lueidum polysaccharide as a non-specific immune stimulating agent is one of the most effective components of Ganoderma lucidum and has a variety of physiological and pharmacological functions,such as scavenging free radicals, anti-aging, anti-tumor and enhancing the body's immunity.The present study was to examine the optimal subcritical water extraction conditions of Ganoderma lucidum polysaccharide by single factor and orthogonal experiment.The results showed that the optimum extraction conditions were as follows: the temperature of subcritical water of 150 ℃, the ratio of solvent to material of 1:12 g/mL, the extraction time and pressure of 5 min and 5 MPa.Under these conditions, the yield of Ganoderma lueidum polysaccharide was 2.15%.Compared with the traditional hot water extraction method, the subcritical water extraction could shorten the extraction time, reduce the cost and improve the extraction yield.

Ganoderma lucidum polysaccharidesubcritical waterextraction

邓辰辰、相继芬、董兴叶、许明君、高如意、徐振秋、肖伟

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江苏康缘药业股份有限公司,江苏 连云港 222001

中药制药过程新技术国家重点实验室,江苏 连云港 222001

中药提取精制新技术重点研究室,江苏 连云港 222001

灵芝多糖 亚临界水 提取

科技部重大新药创制项目现代中药创新集群与数字制药技术平台项目

2013ZX09402203:

2016

河南工业大学学报(自然科学版)
河南工业大学

河南工业大学学报(自然科学版)

CSTPCD北大核心
影响因子:0.547
ISSN:1673-2383
年,卷(期):2016.37(2)
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